Apligraf Bi-Layered Skin Substitute.

Mfg:  Organogenesis.

Size:  Circular disk approximately 75 mm in diameter and 0.75 mm thick

Apligraf^r is supplied as a bi-layered cell therapy. Like human skin, Apligraf consists of living cells and structural proteins. The lower dermal layer combines bovine type 1 collagen and human fibroblasts (dermal cells), which produce additional matrix proteins. The upper epidermal layer is formed by promoting human keratinocytes (epidermal cells) first to multiply and then to differentiate to replicate the architecture of the human epidermis. Unlike human skin, Apligraf does not contain melanocytes, Langerhans' cells, macrophages, and lymphocytes, or other structures such as blood vessels, hair follicles or sweat glands.

Areas of use:  Indicated for use along with standard compression therapy in venous ulcers of at least 1 month in duration that have not adequately responded to conventional ulcer therapy.  Apligraf is also indicated for use with conventional diabetic foot ulcer care for the treatment of full-thickness neuropathic diabetic foot ulcers of greater than three weeks duration which extend through the dermis but without tendon, muscle, capsule or bone exposure.

Apligraf is made in response to demand and is shipped Overnight directly to your facility.  Please order at least 2 business days before the procedure to ensure product availability.  Once your order is placed, one of our Customer Service Representatives will contact you regarding the scheduling for delivery of the product to your facility.

Sold by the Each.

HCPCS CODE # J7340

CPT CODE # 15340\15341